fdamani@cs.princeton.edu

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Hi. I'm Farhan Damani.

I work at the intersection of machine learning and drug discovery. I am broadly interested in tackling design problems using data, models, and computation.

about me.

I recently completed my master's degree in computer science at Princeton University where I worked on problems in computational neuroscience with Jonathan Pillow and Ryan Adams. Previously, I completed my undergraduate degree in computer science at Johns Hopkins University, where I worked with Alexis Battle on understanding the impact of human genetic variation on complex traits using probabilistic modeling. In my earlier years as an undergrad, I worked on robotic grasping and prosthetics development at the Johns Hopkins Applied Physics Lab. My contributions were covered in the JHU Engineering Magazine and in a video with JHU Rising to the Challenge, which you can find here.



Most recently, I have worked on problems in drug discovery including molecular design, reaction condition design, and chemical synthesis design. I also consult for Pfizer R&D on problems in molecular design.

publications.


Black Box Recursive Translations for Molecular Optimization.
Damani F., Sresht V., Ra S.
Under review.
[Manuscript]


Discrete Object Generation with Reversible Inductive Construction
Seff A., Zhou W., Damani F., Doyle A., Adams, R.P.
Neural Information Processing Systems (NeurIPS) 2019
[Manuscript][Code]


Inferring animal learning rules from behavior with probabilistic models.
Damani F., Roy, N., Akrami A., Brody C., Adams, R.P., Pillow, J.W.
Computational and Systems Neuroscience (Cosyne) Extended Abstract.


A framework for predicting tissue-specific effects of rare genetic variants
Damani F., Kim Y., Li X., Tsang E., Davis J., Chiang C., Zappala Z., Strober B., Scott A., Hall I., GTEx Consortium, Montgomery S., Battle A.
In preparation.
[Manuscript][Code][Slides][Talk]


The impact of rare variation on gene expression across tissues
Li X., Kim Y., Tsang E., Davis J., Damani F., Chiang C., Zappala Z., Strober B., Scott A., Ganna A., Merker J., GTEx Consortium, Battle A., Montgomery S.
Nature 2017
[Paper][Code]


The impact of structural variation on gene expression
Chiang C., Scott A., Davis J., Tsang E., Li X., Kim Y., Damani F., Ganel L., GTEx Consortium, Montgomery S., Battle A., Conrad D., Hall I.
Nature Genetics 2017
[Paper]